Susandy Oetama
National Cardiovascular Center Harapan Kita, Indonesia
Title: Sensitivity and specificity of the novel peguero-lo presti left ventricular hypertrophy voltage criterion compared to other criteria: a systematic review
Biography
Biography: Susandy Oetama
Abstract
Left ventricular hypertrophy (LVH) is a well-known risk factor and strong predictor for cardiovascular diseases such as heart failure, coronary artery diseases and stroke. Diagnosing LVH early is clinically important given its massive impact on cardiovascular complications. A good, reliable, and easier diagnosing criterion is needed. This systematic review aims to compare the sensitivities and specificities of several established electrocardiogram voltage criteria, namely the Cornell and Sokolow-Lyon against the newer, supposedly better Peguero-Lo Presti voltage criterion in all adult population. A systematic literature search of articles published between January 1st 2017 and February 28th 2019 according to the PRISMA guideline was conducted. Search engines such as Pubmed, Highwire, CrossRef and ScienceDirect were used. Five studies were included in this review (n = 11,603), all crosssectional, and were assessed using the QUADAS quality assessment tool. Two studies were conducted in hypertensive patients; one study in patients with aortic stenosis; one study was carried out regardless of the diagnosis; and one study was conducted on the general population. Four studies provided evidence that the Peguero-Lo Presti criterion was superior compared to other voltage criteria. Only one study done in Chinese population suggested differently, and the authors proposed a revised cutoff point for the Peguero- Lo Presti criterion to be used in Asian Population. Evidence suggests that the new Peguero-Lo Presti voltage criterion could be a superior alternative in diagnosing LVH in daily practice. However, it may be necessary to modify the cutoff point in order to be used in other population groups as several factors could affect their baseline ECG complexes.